Journal Club Empagliflozin, Cardiovascular Outcomes, And...

JOURNAL CLUB: Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes: EMPAG-REG OUTCOME Danny R. Pate 5/17/16 GENERAL STUDY OVERVIEW Title/Citation Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med 2015;373:2117-28. Journal Reputability High level of Reliability Funding †¢ Boehringer Ingelheim (BI) and Eli Lilly, manufacturers of empagliflozin (Jardiance) and empagliflozin/metformin (Synjardy)were the primary sources of funding for the study †¢ BI paid for medical writing and analyzed the study data, and the study s steering committee included employees of BI †¢ All researchers were paid by either BI or Eli Lilly for either consulting or data monitoring BACKGROUND- THE STUDY QUESTIONS Introduction †¢ Type 2 diabetes is a major risk factor for cardiovascular disease. †¢ There is growing concern that intense glucose lowering or the use of certain agents may be associated with adverse cardiovascular outcomes. †¢ Empagliflozin was compared with placebo and analyzed for effects on morbidity and mortality in patients with T2D at high risk for CV events who were receiving standard of care. Why this study? Empagliflozin has been shown to result in weight loss, reduce blood pressure without increasing heart rate, favorable effects on markers of arterial stiffness and vascular resistance and visceral adiposity. Empagliflozin has also been associated with an increase in both LDL and HDL cholesterol. These surrogate markers

Social Media And Its Effect On Self Image - 1896 Words

Would you consider yourself an important person? The majority of young people in today’s society would say that they indeed are important, as opposed to the very few numbers of people who felt this way in the 1950’s, according to Jean Twenge in her book Generation Me. Debora Lima agrees with Twenge and suggests that this is caused by social media in her article â€Å"Social media plays large part in self image.† Cathy Payne also agrees as she explains the inflation of cosmetic surgeries in her article â€Å"Botox or your bills? Plastic surgery wins out.† Twenge, Payne, and Lima all agree that there is a change in self-image in today’s young society, yet they all argue different sub points on this subject. Overall, there has been a noticeable change in self-image. In chapter 2 â€Å"An Army of One: Me† of Generation Me, Jean Twenge discusses self-image. First, she explains how Gen Me’ers are focused on the self and how their self-esteem is much higher than Baby Boomers’. The author reports how children are encouraged to focus on themselves. This sometimes creates narcissism instead, declares the author. Another thing brought up is how teachers are beginning to not criticize students because it may damage their self-esteem. To conclude, Twenge argues how Gen Me’ers have a positive self-image, but this may not be a good thing (Twenge 44-71). While discussing the change in self-image, Twenge’s target audience is comprised of Gen Me’ers and Baby Boomers. Both of these groups wouldShow MoreRelatedSocial Media Has a Negative Effect on Body Image and Self Esteem1202 Words   |  5 Pages Social media has become one of the most popular sources of communication for the upcoming generation. For young people growing up in today’s society, social media outlets such as Facebook, Instagram and Twitter have provided pictures and news that have become the first thing that their eyes see in the morning and the last thing that they see before bed. These pictures have provided unrealistic standards as to what is considered beautiful in today’s society. As young people refer to these imagesRead MoreSocial Media And Its Effects On Society Essay1605 Words   |  7 PagesOver the duration of time, I have noticed the great deal of power that media has influenced on how women ought to appear. The relationship between social media and its users is a high effect on people and causes many problems. We are constantly thrown images of women and men to categorize what is eye catching. It has been clear that social media has blossomed in the last few decades to only deliver u s with messages. Social media is applying to us, that looking more like the Kardashians and less likeRead MoreSocial Media Allows People To Share Pictures And Ideas1057 Words   |  5 PagesSocial media allows people to share pictures and ideas with others across the world. 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Acts of congress summary Free Essays

Politics First Chapter Nine continues with an examination of Barney Frank, the Democrat who served as the senior leader of the House Financial Services Committee that was responsible with researching, marking up, rewriting, and passing proposed legislation that would prohibit another financial crisis from developing in the future. However, while waiting for the release the administration’s white paper, which helped inform and educate members of Congress about White House proposals, Frank found himself in the midst of a potential political rebellion from in Congress, nd even from within his own party. Many moderates balked at Franks more aggressive reform proposals, while liberals found it treasonous that he was collaborating with banks, the very institutions that they held responsible for the onset of the financial crisis and the beneficiaries of TARP†Troubled Asset Relief Program. We will write a custom essay sample on Acts of congress summary or any similar topic only for you Order Now One such critic was Senator Dick Durban, who rejected the idea ofa bank bail-out, and was disappointed that banks were still in a position to politic in Washington. Frank disagreed, asserting that the big banks were losing steam in Washington and the evidence was simple: they could not prohibit the passage of redit card legislation that protected consumers. In an effort to gain support and educate members of Congress, Franks staff put on a serious of workshops and work sessions for members. In addition to his efforts to placate liberals, Frank threw his support behind provisions that would ultimately become the Consumer Financial Protection Bureau†an idea first presented by Elizabeth Warren in an article for the journal Democracy. The legislation became important but the â€Å"blues and news,† the old and new moderate factions of the Democratic party of each party, were already rowning in health care legislation, breaking Franks declaration that the new legislation would pass before Congress’ summer vacation. Key Points/Details Big banks were largely to blame, but collateral damage of the bank fallout could be small banks and credit unions – The press was largely to blame, in Franks mind, for overstating the political clout that big banks and Wall Street had What would their influence be in the process of writing new legislation – Frank recruited the Democratic members of the House Committee on Financial Services (Banking Committee) who he held in highest esteem to work on issues for the reform bill – Frank favored three hallmarks for reform that might relieve liberals who were nervous that banks were not bearing the brunt of responsibility for the crisis o Credit card bill – more transparency from issuers of credit cards o Subprime mortgage bill – bill that banned many subprime mortgages and required that lenders would require companies to give stockholders a chance to give feedback about Though Frank had originally been hesitant to support such a executive pay – provision, White House backing, growing support from among popular and powerful Democrats (Clinton, Edwards, etc. polling numbers that seemed to indicate that the public favored it, and convincing arguments from Harvard law professor – and current US Senator from Massachusetts – Elizabeth Warren, persuaded Frank to throw his support behind the creation of a new regulatory agency (CFPA/b). Agency would regulate American financial firms and the services and products that they offer to the public – Independent agency under the Federal Reserve Board o Frank felt pressure from both sides – the administration as well as hesitant, moderate â€Å"news and blues† – of his own party Many were worried that supporting the creation of he agency would leave them vulnerable in upcoming elections in vulnerable districts o Proposed health care and â€Å"cap and trade† legislation distracted both Congress and the public – Frank began to recognize that he had to do more to reassure his colleagues that this agency was a good idea Worked to cajole them and gain their support o By the end of the chapter, Frank is convinced that he is right and that he will be able to get such legislation passed Terms: derivatives rating agencies systemic risk regulator subprime mortgages consumer protection â€Å"say on pay’ Elizabeth Warren Price gouging Payday lender Office of Legislative Council CFPA / CFPB Chapter 10 – An Impotent Minority Chapter 10 focuses on the struggles of Rep. Spencer Bachus (R-AL) and the rest of his party to reconcile their desire to reform the financial sector but not seem to bow to the desires of the Democrats. Rep. Bachus, a moderate Republican who before the crash had proposed legislation regulating subprime mortgages only to be rebuffed by his more conservative colleagues, favored bipartisan efforts. He was up against an increasingly conservative House Republican caucus, who were led by radicals who ere emboldened by redistricting in their states that left them with little need to proposal for financial reform, undercutting the release of the administration white paper by a week. This proposal overwhelmingly focused on the principle that they would not stand for future â€Å"bailouts† of the Wall Street institutions that were responsible for the financial crisis. Though the plan garnered little media attention, and did not include many of the provisions laid out in the White House bill, it did indicate that Congressional Republicans recognized the reality that comprehensive financial reform was necessary. TARP Republican Study Committee How to cite Acts of congress summary, Papers

Case Study Word’s Smith Limited

Question: Case study on "Words Smith Limited". Answer: Words Smith limited can achieve an improved HRMIS planning by allocating appropriate workforce for different job roles. The workforce of the company needs to be configured in such a way that the identification of the employees for specialized job roles becomes easy. The employee details should be updated based on the qualifications of the employees of mainly bookstore. The understanding of the employee requirement based on the qualification would ensure the proper segregation of workers according to part-time and full time positions. The workforce data based on the qualification of the employees will help in downsizing the company workforce (Yusof Aziz, 2015). The workforce details of the employees should be directly linked to performance evaluation of the employees, which will enable the management to consider various restructuring decision in future. The information from the performance evaluation technique can provide valuable information in assessing the most efficient employees for timely delivery of tasks. In this way the employees with greater efficiency can be allocated to a part time job role as they can complete an order processing in shortest time possible. Words Smith existing database should be updated along with mainly bookstore and with this amalgamation the qualification of the employees should also be updated. This strategy of workforce information will facilitate greater flexibility in decision making in terms of the job allocation of the employees in different department within the existing retail chain locations. In order to ensure the complete updating procedure, the employees should be informed to update their academi c background, Alma matter, past experience and key skills. The improvement in the existing HRMIS system can be brought by recognizing the employees best suited for a particular job role. This will enable the employees to be allocated in specialized departments of Words Smith limited. The downsizing process through converting the full time employees into part-time employees would ensure that not only the cost is reduced but the efficient allocation of the employees into specific job roles would help the company perform in a better way and meet the targets in time of seasonal fluctuation. The reallocation of the employees into part-time and full time through HRMIS would also prevent the company to retrench the existing employees for the existing companies (Yu, 2012). Reference List Yu, Y. (2012, May). The Progress of Human Resource Management Information System. In Proceedings of the 2012 3rd International Conference on E-Business and E-Government-Volume 03 (pp. 1093-1096). IEEE Computer Society. Yusof, M. M., Aziz, K. A. (2015). Evaluation of Organizational Readiness in Information Systems Adoption: A Case Study. Asia-Pacific Journal of Information Technology and Multimedia, 4(2).